Jan 20, 2023 Leave a message

Overview of polycrystalline cellulose

The First Clinical College of Dalian Medical University and the Dalian Institute of Chemical Physics of the Chinese Academy of Sciences (hereinafter referred to as the Dalian Institute of Chemical Physics), after many years of cooperation, have developed a new high-tech material - polycrystalline cellulose, which can be used to prevent tissue adhesion after creation and hand surgery, and has proved its good adhesion effect in basic experiments and clinical application studies.

How to make the surgical operation not only achieve the treatment of diseases but also not cause serious adhesion complications is an urgent problem to be solved in today's surgery. From 1993 to 1999, the research group led by Professor Jiang Changming of orthopedics developed a new type of absorbable anti-adhesion material - poly cellulose (poly CMC), which has carried out extensive basic and clinical prospective research in orthopedics, general surgery, neurosurgery and other disciplines. In the basic research, they cooperated with Dalian Institute of Chemical Sciences and successfully completed the synthesis and drug screening of polycellulose using polycellulose as raw material and polyglucose as cross-linking agent. Animal experimental studies have been carried out to prevent adhesion of tendon, nerve, dura mater, joint and abdominal cavity after operation, and it has been proved that the effect of prevention of adhesion is obvious. The clinical application study observed the effect of poly-polymer fiber on preventing muscle adhesion. Polycellulose has good biocompatibility and is an ideal anti-adhesion material. It can eliminate or reduce postoperative complications caused by adhesion, and reduce operative mortality and disability rate.

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